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. 2011 Sep 15;12(6):549–555. doi: 10.4161/cbt.12.6.16397

Figure 6.

Figure 6

BEZ235 and CQ combination results in enhanced inhibitory effects on the growth of lung cancer xenograpts in mice. Mice with A549 xenograpts were treated with vehicle control, CQ (50 mg/kg) alone, BEZ-235 (30 mg/kg) alone and BEZ-235 plus CQ on the same day after grouping. After 16-d consecutive treatment (once daily), the mice were sacrificed. Tumor sizes (A) and body weight (B) were measured once every 2 d. Each measurement is a mean ± SD (n = 6). *p <0.001 compared with the vehicle control.