Table 3.

Main Associations of 5 Single Nucleotide Polymorphisms Previously Associated With Glioma in Non-Hispanic White Women From 4 US Studies^a, 1993–2001

SNP and Genotype	Controls		Cases		Odds Ratio	95% Confidence Interval	P Value
	No.	%	No.	%
rs2736100
GG	197	24	69	21	1.00	Referent
GT	401	49	172	52	1.27	0.90, 1.79	0.2
TT	217	27	91	27	1.22	0.83, 1.80	0.3
GT + TT	618	76	263	79	1.25	0.91, 1.73	0.2
P for trend							0.3
rs4295627
TT	556	68	187	56	1.00	Referent
GT	242	30	121	36	1.47	1.11, 1.97	0.008
GG	19	2	24	7	3.51	1.81, 6.82	0.0002
GT + GG	261	32	145	44	1.63	1.23, 2.14	0.0005
P for trend							0.00004
rs4977756
AA	303	37	113	34	1.00	Referent
AG	389	48	151	45	1.05	0.78, 1.42	0.7
GG	125	15	68	20	1.58	1.07, 2.33	0.02
AG + GG	514	63	219	66	1.17	0.89, 1.55	0.3
P for trend							0.04
rs498872
CC	401	49	150	45	1.00	Referent
CT	338	41	149	45	1.22	0.91, 1.62	0.2
TT	77	9	32	10	1.13	0.70, 1.82	0.6
CT + TT	415	51	181	55	1.20	0.92, 1.57	0.2
P for trend							0.3
rs6010620
GG	472	58	218	66	1.00	Referent
AG	296	36	99	30	0.72	0.54, 0.97	0.03
AA	49	6	15	5	0.63	0.34, 1.18	0.2
AG + AA	345	42	114	34	0.71	0.53, 0.94	0.02
P for trend							0.02

Abbreviation: SNP, single nucleotide polymorphism.

^aData were adjusted for age at diagnosis, study, and educational level.