Table 2.

Percentage of Volunteers With Local Reactogenicity at Any Clinic Visit (Intent-to-Treat Cohort)

	Dryvax	LC16m8
	(n = 28)	(n = 125)	P value
Local reactogenicity	68% (19/28)	82% (102/125)	.12
Warmth	39% (11/28)	36% (45/125)	.83
Tenderness at vaccination site	46% (13/28)	42% (52/125)	.68
Limited arm motion	18% (5/28)	12% (15/125)	.37
Axillary lymph node(s) swollen	46% (13/28)	37% (46/125)	.39
Axillary lymph node(s) tender	50% (14/28)	48% (60/125)	1.00
Rash	4% (1/28)	2% (3/125)	.56
Satellite lesion	0% (0/28)	2% (3/125)	1.00

Volunteer is counted once at the highest level of severity for each reactogenicity category.