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. 2010 Oct;88(4):699–706. doi: 10.1189/jlb.0309185

Figure 6. Lnk inhibits M-CSF-triggered migration of macrophages.

Figure 6.

Peritoneum-derived macrophages from Lnk KO and WT mice were plated in serum-free medium in the upper chamber of a transwell. The lower chamber contained serum-free medium with (+) or without (–) M-CSF or medium supplemented with 10% FCS. Migration capacity was measured by counting cells adhering to the lower side of the membrane after a 20-h incubation period. The graph shows means and sd of 3 independent experiments. The percentage of migrated macrophages was normalized to the number of migrated Lnk KO cells toward M-CSF.