Figure 5.
Effect of suppression of NF-κB p65 by siRNA on cell morphology and cell survival. A) Cell morphology. After RNA interference, cells were treated with 2 ng/mL cytokines for 2 days (original magnification ×400). B) Cell length. Values are means ± SD of 3 separate experiments. C) Cell survival. After RNA interference, cells were treated with 2 ng/mL cytokines in serum and growth factor-free medium for 4 days (original magnification ×200).
Notes: *P < 0.05 compared with control; **P < 0.05 compared with cells treated with IL-1β; +P < 0.05 compared with same cytokine treatment transfected with nontargeting siRNA.