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. 2010 Mar 26;3:51–63. doi: 10.2147/prbm.s7072

Table 4.

Sedatives used in dermatologic conditions

Category Agent Dosage Side effects Cautions
Antihistamines Certirizine (Zyrtec®) 10 mg daily Sedative Use caution driving
Diphenhydramine (Benadryl®) 25–50 mg tid–qid Sedative With each
Doxepin (Sinequan®) 25–100 mg tid Sedative
Hydroxyzine (Atarax®) 25–100 mg tid Sedative
Levocetrizine (Xyzal®) 5 mg daily Mild sedative
Promethazine (Phenergan®) 25–100 mg tid–qid Sedative
Herbs Valerian 300–900 mg daily HS
Supplements Melatonin 3 mg HS
Nondrug Hypnosis HS Avoid use driving
Progressive relaxation HS

Abbreviations: HS, at bedtime; qid, four times daily; tid, three times daily.