Table 1.
Demographic data at baseline
| Early stage | Middle stage | Late stage | Overall | |
|---|---|---|---|---|
| Age (years) | 74.1 (7.91) | 76.3 (7.12) | 78.3 (6.07) | 75.7 (7.4) |
| Gender, female | 84 (52.2%) | 100 (57.1%) | 41 (67.2%) | 225 (56.7%) |
| White | 161 (100.0%) | 175 (100.0%) | 61 (100.0%) | 397 (100%) |
| Weight (kg) | 74.0 (13.7) | 72.0 (15.1) | 67.6 (11.5) | 72.1 (14.1) |
| Height (cm) | 167.0 (8.9) | 165.1 (9.1) | 164.0 (8.1) | 165.7 (8.89) |
| MMSE score | 23.3 (4.2) | 18.6 (5.2) | 12.5 (5.5) | 19.6 (6.1) |
| ADAS-cog score | 16.3 (6.4) | 23.4 (8.4) | - | 20.0 (8.3) |
| SIB scorea | - | 79.1 (11.3) | 62.6 (20.3) | 74.7 (16.0) |
| DAD score | 33.3 (6.8) | 24.7 (9.4) | 13.8 (8.3) | 26.4 (10.6) |
| NPI score | 9.7 (9.6) | 14.1 (11.7) | 22.2 (14.4) | 13.9 (12.3) |
Data presented as mean (standard deviation) or number (%) of patients (full analysis set). ADAS-cog, Alzheimer's Disease Assessment Scale - cognitive subscale; DAD, Disability Assessment for Dementia; MMSE, Mini-Mental State Estimation; NPI, Neuropsychiatric Inventory; SIB, Severe Impairment Battery.aQuestions 1, 39, and 40 were omitted in this study.