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Major factors affecting phenotypic variability in mice
| Environmental |
| Housing system (type of caging/enrichment) |
| Housing density (number of mice per cage) |
| Handler/Investigator |
| Light cycle |
| Temperature and humidity |
| Noise and vibration |
| Diet |
| Health status |
| Biological |
| Age |
| Sex |
| Body condition |
| Genetic drift |
| Genetic background (mixed versus inbred) |
| Type of background strain |
| Transgene copy number |
| Transgene expression level |
