Table 4.
Summary of parameter estimates and significance levels of the multivariate linear regression analysis for the CpG transition/transversion rate ratio (κ)
| Dataset A | Dataset B | Dataset C | ||||
|---|---|---|---|---|---|---|
| Estimate | -log10(p) | Estimate | -log10(p) | Estimate | -log10(p) | |
| Divergence | 0.2574 | 15.20 | 0.1450 | 9.54 | 0.2093 | 8.46 |
| Methylation level | 0.1666 | 6.79 | 0.3116 | > 15.70 | 0.8127 | > 15.70 |
| GC content | 0.2478 | 13.98 | 0.0257 | 0.57 | -0.1815 | 5.84 |
| Transcription level | -0.1744 | 7.31 | -0.0294 | 0.69 | 0.0871 | 1.77 |
| Female recombination rate | -0.0321 | 0.48 | 0.0533 | 1.60 | 0.0210 | 0.25 |
| Male recombination rate | 0.0971 | 2.49 | 0.0642 | 2.13 | -0.0130 | 0.14 |
| Explained variance | 3.97% | 1.73% | 17.73% | |||
| na | 5,550 | 14,165 | 3,376 | |||
Dataset A contains no CpG islands (CGIs) or DNase I hypersensitive sites (DHSs)), dataset B contains DHSs but no CGIs, and dataset C contains both CGIs and DHSs. aSample size.