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Predictive value of circulating tumor cells. Comparison of different first-line treatments according to circulating tumor cell (CTC) baseline value. (a) Combination chemotherapy (poly-CTx) versus single-agent chemotherapy (mono-CTx). (b) Monochemotherapy + bevacizumab (CTx + bev.) versus single-agent chemotherapy (mono-CTx). CI, confidence interval; IV, inverse variance; SE, standard error.
