Table 4.
Donor kidney biopsy findings in the high and low NGAL groupsa
| Serum NGAL | Urine NGAL | |||||
|---|---|---|---|---|---|---|
| Biopsy findings | High, ≥214 ng/mL (n = 38) |
Low, < 214 ng/mL (n = 57) |
P value | High, ≥18 ng/mL (n = 26) |
Low, < 18 ng/mL (n = 69) |
P value |
| Tubulitis | 0 (0%) | 0 (0%) | NS | 0 (0%) | 0 (0%) | NS |
| Intimal arteritis | 0 (0%) | 0 (0%) | NS | 0 (0%) | 0 (0%) | NS |
| Interstitial inflammation | 1 (2.6%) | 0 (0%) | NS | 1 (3.4%) | 0 (0%) | NS |
| Glomerulitis | 0 (0%) | 0 (0%) | NS | 0 (0%) | 0 (0%) | NS |
| Interstitial fibrosis | 3 (7.9%) | 2 (3.5%) | NS | 3 (10.3%) | 2 (3.0%) | NS |
| Tubular atrophy | 3 (7.9%) | 3 (5.3%) | NS | 3 (10.3%) | 2 (3.0%) | NS |
| Glomerulopathy | 3 (7.9%) | 3 (5.3%) | NS | 3 (10.3%) | 2 (3.0%) | NS |
| Mesangial matrix increase | 1 (2.6%) | 0 (0%) | NS | 1 (3.4%) | 0 (0%) | NS |
| Intimal thickening | 11 (28.9%) | 14 (24.6%) | NS | 9 (31.0) | 15 (22.7%) | NS |
| Arterial hyalinosis | 8 (21.1%) | 13 (22.8%) | NS | 8 (27.5%) | 15 (22.7%) | NS |
| CADI score, n | ||||||
| 0 or 1 | 30 | 46 | NS | 17 | 61 | 0.010 |
| ≥2 | 8 | 11 | 9 | 8 | ||
aCADI, Chronic Allograft Damage Index [31]; NGAL, neutrophil gelatinase-associated lipocalin.