Table 2.

Therapeutic interventions in the study population^a

Interventions	rhTM group (n = 20)	Control group (n = 45)	P value
Mechanical ventilation, %	20 (100)	45 (100)	n.s.
Shock, %	15 (75)	32 (71)	n.s.
Use of any vasopressor, %	13 (65)	33 (73)	n.s.
Infusion within 24 hours, mL	8,600 (6,400 to 13,500)	7,600 (4,200 to 11,500)	n.s.
Antibiotics administration within 3 hours of enrollment, %	20 (100)	45 (100)	n.s.
Appropriateness of antibiotic therapy, %	16 (80)	37 (82)	n.s.
Use of low-dose steroid, %	3 (15)	14 (31)	n.s.
Renal replacement therapy, %	9 (45)	16 (36)	n.s.

^arhTM, recombinant human soluble thrombomodulin; n.s., not significant. Data are expressed as group medians (interquartile range) or number (percent).