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. 2011 Jun 6;15(3):R136. doi: 10.1186/cc10254

Table 4.

Diagnostic value of the various parameters studied

CSF parameters Serum parameters CSF/serum ratio
Neutrophil/mm3 Protein g/L Glucose mmol/L Lactate mmol/L PCT ng/ml CRP mg/l Glucose CSF/serum Lactate CSF/serum

AUC 0.86 0.93 0.69 0.96 0.99 0.92 0.87 0.84
[CI 95%] [0.86-0.94] [0.92-0,98] [0.69-0.76] [0.95-1] [0.99-1] [0.92-0.98] [0.86-0.91] [0.84-0.93]
Optimal cut-point 118 1.88 2.2 3.8 0.28 37 0.48 2.22
Sensitivity 0.80 0.89 0.97 0.94 0.97 0.86 0.84 0.79
Specificity 0.85 0.93 0.49 0.97 1 0.84 0.89 0.89
Positive predictive value 0.47 0.67 0.92 0.82 0.97 0.46 0.98 0.52
Negative predictive value 0.96 0.98 0.71 0.99 1 0.97 0.66 0.97
Global value 0.84 0.92 0.90 0.96 0.99 0.84 0.76 0.87

AUC, area under a curve; CI, confidence interval; CSF, cerebrospinal fluid.