Figure 1.

Study inclusion and exclusion criteria flowchart. This flowchart illustrates the inclusion and exclusion criteria used to screen patients from both study centers to derive the final study population. ¹Centre Hospitalier Universitaire Ste-Justine (CHUSJ) original exclusion criteria were < 3 days of age or < 40 weeks of gestation, > 18 years of age, pregnancy or postpartum admission, admission for renal transplantation, brain death at entry into the pediatric intensive care unit (PICU), expected PICU stay < 24 hours, a priori decision to withhold or withdraw treatment and end-stage renal failure. hrs = hours; Jan = January; MCH = Montreal Children's Hospital; Sep = September.