Table 2.
Distribution of infections, infection characteristics, and pathogens for main and sepsis population
| Main population | Sepsis population | |||
|---|---|---|---|---|
| ♂ | ♀ | ♂ | ♀ | |
| Number | 400 | 309 | 197 | 130 |
| Patients with infections n (%) | 248 (62.0%)a | 164 (53.1%)a | 197 (100%) | 130 (100%) |
| Colitis, pseudomembranous | 2 (0.5%) | 3 (1.0%) | 2 (1.0%) | 2 (1.5%) |
| Pneumonia | 135 (33.8%)a | 75 (24.3%)a | 124 (62.9%) | 70 (53.8%) |
| Lower urinary tract infections | 13 (3.3%)a | 34 (11.0%)a | 11 (5.6%)a | 30 (23.1%)a |
| Bones and joints | 11 (2.8%) | 7 (2.3%) | 8 (4.1%) | 6 (4.6%) |
| Endocarditis | 11 (2.8%) | 7 (2.3%) | 10 (5.1%) | 6 (4.6%) |
| Abdomen | 40 (10.0%) | 28 (9.1%) | 32 (16.2%) | 18 (13.8%) |
| Soft tissue and wounds | 80 (20.0%) | 47 (15.2%) | 55 (27.9%) | 38 (29.2%) |
| Upper urinary tract infections | 6 (1.5%) | 4 (1.3%) | 3 (1.5%) | 1 (0.8%) |
| Meningitis | 5 (1.3%) | 5 (1.6%) | 4 (2.0%) | 3 (2.3%) |
| Bloodstream infection | 35 (8.8%) | 17 (5.5)%) | 34 (17.3%) | 16 (12.3%) |
| Fever of unknown origin | 33 (8.3%) | 24 (7.8%) | 22 (11.2%) | 17 (13.1%) |
| Catheter-related infections | 17 (4.3%) | 5 (1.6%) | 17 (8.6%) | 5 (3.8%) |
| SIRS occurrence n (%) | 364 (91.0%) | 290 (93.9%) | 197 (100%) | 130 (100%) |
| Sepsis occurrence n (%) | 197 (49.3%) | 130 (42.1%) | 197 (100%) | 130 (100%) |
| Severe sepsis occurrence n (%) | 89 (22.3%)a | 48 (15.5%)a | 89 (45.2%) | 48 (36.9%) |
| Septic shock occurrence n (%) | 74 (18,5%) | 41 (13,3%) | 74 (37.6%) | 41 (31.5%) |
| Fungi detected | 64 (16.0%) | 47 (15.2%) | 61 (31.0%) | 42 (32.3%) |
| Gram-negative germs detected | 98 (24.5%) | 58 (18.8%) | 89 (45.2%) | 52 (40.0%) |
| Difficult-to-treat bacteria detected | 41 (10.3%) | 28 (9.1%) | 37 (18.8%) | 26 (20.0%) |
aP < 0.05 in a two-tailed χ2 test. More than one infection period per patient was possible. Difficult-to-treat pathogens include bacteria associated with potential intrinsic or acquired resistance (methicillin-resistant Staphylococcus aureus, germs producing extended spectrum betalactamases, Vancomycin-resistant Enterococci, nonfermenters like Pseudomonas spp., Stenotrophomonas maltophilia, Acinetobacter baumanii, Citrobacter spp., Enterobacter cloacae, Enterococcus faecium, and Bacillus cereus). Binary parameters presented in total and percentage (%). SIRS, systemic inflammatory response syndrome.