Table 2.
Crude OR of clinical and biochemical variables for death (GOS 1) in hospital and six months after severe traumatic brain injury using univariate logistic regression
| In Hospital Mortality | 6 months Mortality | |||
|---|---|---|---|---|
| Variable | OR (95%CI) | C | OR (95%CI) | C |
| UCH-L1 | 2.74 (1.54-4.90)* | 0.74 | 2.29 (1.07-4.90)† | 0.62 |
| GFAP | 1.41 (1.08-1.84)† | 0.76 | 3.30 (1.21-8.50)† | 0.75 |
| Age | 1.02 (0.99-1.05) | 0.60 | 1.07 (1.03-2.11)* | 0.78 |
| GCS | 0.64 (0.45-0.91)† | 0.69 | 0.59 (0.41-0.85)† | 0.72 |
| Gender | ||||
| Female | Reference | Reference | ||
| Male | 1.01 (0.80-1.29) | 0.60 | 0.69 (0.19-2.58) | 0.53 |
| Marshall Score | ||||
| I-II | Reference | Reference | ||
| III-IV | 9.80 (1.50-63.83)† | 12 (1.58-91.08)† | ||
| V-VI | 2.80 (0.55-14.23) | 0.67 | 5.56 (1.25-24.77)† | 0.67 |
C = The area under an receiver operating characteristic curve (also known as c-statistic) provides an overall measure of classification accuracy (representing the overall proportion of individuals correctly classified), with the value of one representing perfect accuracy.
* P < 0.001, † P < 0.01
GCS: Glasgow Coma Scale score; GFAP: glial fibrillary acidic protein; GOS: Glasgow Outcome Scale; OR: odds ratios; UCH-L1: Ubiquitin C-terminal Hydrolase-L1 protein.