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. 2011 Oct 13;2(10):e216. doi: 10.1038/cddis.2011.97

Figure 7.

Figure 7

Inhibitory concentration determination for lysosomotropic compounds. IC50 determination was carried out on (a) 3D7, (b) 7G8 and (c) K1 parasites that were incubated for 48 h with various concentrations of the test compounds. Compounds tested were CQ, DSP, CPZ, PMZ and 4HT. Parasitemia was determined using Hoechst staining and flow cytometric analyses