Figure 7.
Inhibitory concentration determination for lysosomotropic compounds. IC50 determination was carried out on (a) 3D7, (b) 7G8 and (c) K1 parasites that were incubated for 48 h with various concentrations of the test compounds. Compounds tested were CQ, DSP, CPZ, PMZ and 4HT. Parasitemia was determined using Hoechst staining and flow cytometric analyses