Table 1.

Expressions of relevant genes to pancreatitis

Gene transcripts	WT (−)	WT (pIC)	Irf2−/−(−)	Irf2−/− (pIC)
Prss1 (T16, Trypsin1)	11,161	13,863	10,388	13,788
Prss2 (T20, Trypsin 2)	16,041	15,661	15,857	15,494
Prss3 (T11, Trypsin 3)	1,155	1,131	3,059 ↑	2,395 ↑
Trypsinogen5 (T4, 1810009J06Rik)	70	57	13,514 ↑	14,287 ↑
Chymotrypsin C (Ctrc)	545	368	87 ↓	119 ↓
Chymotrypsinogen B 1 (Ctrb1)	19,417	18,772	20,457	19,919
Amylase2-2, pancreatic (Amy2b)	19,101	18,488	17,092	18,261
Calcium-sensing receptor (Casr)	37	37	30	26
Cystic fibrosis membrane conductance regulator (Cftr)	7	6	11	8
Cathepsin B (Ctsb)	349	443	848 ↑	794 ↑
Serine protease inhibitor, Kazal-type 3 (Spink3)	4,716	3,957	7,497	7,774
Inter-α-trypsin inhibitor, heavy chain 4 (Itih4)	375	212	78 ↓	71 ↓
Galanin (Gal)	879	1,057	213 ↓	71 ↓

The levels of gene expression in the pancreas are shown in Affymetrix units. The trypsinogen5 data are Point 1 in Fig. 2.