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. 2011 Oct 27;108(46):E1164–E1173. doi: 10.1073/pnas.1112304108

Table 3.

Summary of fetoplacental phenotypes from syncytin KO mice

syncytin-A KO syncytin-B KO
100% embryonic lethality (midgestation) 20% reduced proportion of neonates (late gestation)
Growth retardation (early gestation) Growth retardation (late gestation)
Trophoblast overexpansion No trophoblast accumulation
Squeezed fetal vessels Enlarged maternal lacunae
Unfused ST-I Unfused ST-II