Fig. 2.

Neuronal progenitor cell numbers are reduced in the Neil3-deficient striatum after HI. (A) Cellularity in the SVZ after HI. The images represent Neil3^+/+. Bar graphs display densiometric quantification of fluorescent intensity measured in two nonadjacent coronal sections from each animal. Fold change from sham-treated animals was calculated. (B and C) Neuronal progenitors (DCX⁺) in striatal tissue 3 d (B) and 10 d (C) after injury. NeuN⁺/DCX⁺ neuronal progenitors are indicated by arrows. (B) *P = 0.027. (C) *P = 0.049; **P = 0.011. Cells were counted in two nonadjacent sections from each animal. (A–C) n = 4–5 mice. Data represent mean ± SEM. (Scale bars, 20 μm.)