Table 2.
Sera reacting with MUC1 glycoforms when screened against arrays displaying glycoforms shown in Figure 1B
| Sera from patients with benign breast disease used to define cut-off | Sera from age-matched healthy females used to define cut-off | |||
|---|---|---|---|---|
| P < 0.0001 | P = 0.0007 | |||
| Breast cancer n (%) | Benign disease n (%) | Breast cancer n (%) | Healthy females n (%) | |
| negative | 271 (69) | 97 (90) | 272 (69) | 85 (86) |
| positive1 | 124 (31) | 11 (10) | 123 (31) | 14 (14) |
| strong positive2 | 97 (24) | 8 (7) | 80 (20) | 7 (7) |
1Sera was defined as positive if it was two standard deviations or higher than the mean fluorescence for at least one feature.
2 Sera was defined as strong positive if four standard deviations or higher than the mean fluorescence for at least one feature