Table 3.
Autoantibodies in cancer patient sera to MUC1 glycoforms correlate with age when sera were taken
| Sera from patients with benign breast disease used to define cut-off | Sera from age-matched healthy females used to define cut-off | ||||
|---|---|---|---|---|---|
| All positives1 | Strong positives2 | All positives | Strong positives | ||
| P = 0.001 | P = 0.001 | P = 0.007 | P = 0.003 | ||
| Age sera taken | N | n (%) | n (%) | n (%) | n (%) |
| <50 | 633 | 7 (11) | 3 (5) | 14 (22) | 5 (8) |
| 50 to 59 | 132 | 33 (25) | 27 (20) | 31 (24) | 21 (16) |
| 60 to 69 | 136 | 57 (42) | 46 (34) | 51 (38) | 39 (29) |
| 70+ | 64 | 27 (42) | 21 (33) | 27 (42) | 15 (23) |
1 Sera were defined as all positive if two standard deviations or higher than the mean fluorescence for at least one feature.
2 Sera was defined as strong positive if four standard deviations or higher than the mean fluorescence for at least one feature.
3 Total number in age group