Table 4.

Femur bone geometry in 18-wk-old mice

Parameter	Pkd1flox/+	Dmp1-Cre; Pkd1flox/+	Pkd1flox/m1Bei	Dmp1-Cre; Pkd1flox/m1Bei
Total area (mm2)	2.1 ± 0.16	2.2 ± 0.14	1.9 ± 0.11*	1.7 ± 0.13*,#
Cortical area (mm2)	1.03 ± 0.09	1.08 ± 0.08	0.99 ± 0.05	0.98 ± 0.08
Moment of inertia, Ix (mm4)	0.19 ± 0.03	0.21 ± 0.02	0.17 ± 0.02	0.14 ± 0.02*,#
c (mm)	0.71 ± 0.05	0.70 ± 0.04	0.68 ± 0.04	0.63 ± 0.03*,#

c, distance from the neutral axis to the plane where the load is applied. Data are means ± sd from 5 to 6 individual mice.

^*P < 0.05 vs. Pkd1^flox/+ and Dmp1-Cre;Pkd1^flox/+;

^#P < 0.05 vs. Pkd1^flox/m1Bei.