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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Free Radic Biol Med. 2011 Sep 10;51(11):2041–2047. doi: 10.1016/j.freeradbiomed.2011.09.001

Fig. 2. CYP3A4 expression alters the secretion of key autocrine and paracrine factors.

Fig. 2

HepG2 cells were infected with control adenovirus (AdRSV) or adenovirus encoding for CYP3A4 (Ad3A4) at MOIs of 25, in the presence (NAC) or absence (−) of 5 mM N-acetylcysteine. Columns and crossbars represent the mean and SE, respectively, of four replicate samples, each prepared from a seperate cell culture dish. a and b indicated that the treatment mean is statistically different (p < 0.05) from the AdRSV or the Ad3A4 group, respectively, based on ANOVA and Fisher’s test. Data are representative of duplicate studies conducted on separate days.