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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Free Radic Biol Med. 2011 Sep 10;51(11):2041–2047. doi: 10.1016/j.freeradbiomed.2011.09.001

Fig. 5. NF-κB Activity is Required for CYP3A4 Induction of PDGF Secretion in HepG2 Cells.

Fig. 5

HepG2 cells were transduced with the adenoviral vector (AdRSV) or virus expressing CYP3A4 (Ad3A4) at MOIs of 25. Fresh medium was added with or without 1 μM NF-κB Activity Inhibitor I (NAI) and medium was collected 6 h later. Columns and crossbars represent the mean and SE, respectively, for 4 individual samples, each of which was collected from a separate dish. a and b indicated that the treatment mean is statistically different (p < 0.05) from the AdRSV or the Ad3A4 group, respectively, based on ANOVA and Fisher’s test. Data are representative of duplicate studies conducted on separate days.