Table 3.
Positive culture at enrollment | P value | New positive culture following enrollment | P value | |||
---|---|---|---|---|---|---|
Placebo N = 25 |
Heparin N = 25 |
Placebo N = 25 |
Heparin N = 25 |
|||
Respiratory cultures, number (percentage) | ||||||
Pathogen detected | 11 (44) | 5 (20) | 0.07 | 12 (48) | 9 (36) | 0.4 |
Gram-positive | 4 (16) | 1 (4) | 0.4 | 1 (4) | 2 (8) | 0.5 |
Gram-negative | 5 (20) | 1 (4) | 0.2 | 6 (24) | 5 (20) | 0.7 |
Yeast/fungus | 3 (12) | 1 (4) | 0.6 | 7 (28) | 3 (7) | 0.2 |
Legionella pneumonia | 1 (4) | 0 | 1 | 0 | 0 | |
H1N1 polymerase chain reaction | 1 (4) | 2 (8) | 1 | 0 | 0 |
Pulmonary lavage was undertaken at enrollment and on study days 1, 2, 4, 8, and 14 if the patient remained ventilated and sedated.