Table 6.
Multiple regression models for in-hospital mortality and survival time using an APACHE III-based marker of severitya
| Variable | Hospital mortality OR (95% CI) |
P value | Time to death HR (95% CI) |
P value |
|---|---|---|---|---|
| AP3no-oxb | 1.5 (1.5 to 1.6) | <0.0001 | 1.2 (1.2 to 1.2) | <0.0001 |
| Treatment limitationc | 5.3 (3.8 to 7.2) | <0.0001 | 1.7 (1.5 to 1.8) | <0.0001 |
| Year of admission | 0.9 (0.9 to 0.9) | <0.0001 | 0.97 (0.96 to 0.98) | <0.0001 |
| Lowest glucose in first 24 hours | 1.1 (1.1 to 1.1) | <0.0001 | 1.02 (1.02 to 1.03) | <0.0001 |
| Hospital admission from home | 1.3 (1.1 to 1.4) | 0.0002 | 1.1 (1.0 to 1.1) | 0.02 |
| Hypoxia/poor O2 exchange versus normoxia | 1.2 (1.1 to 1.4) | 0.002 | 1.1 (1.0 to 1.2) | 0.01 |
| Hyperoxia versus normoxia | 1.2 (1.0 to 1.5) | 0.04 | 1.1 (1.0 to 1.2) | 0.20 |
aAPACHE III, Acute Illness Severity and Chronic Health Evaluation III; OR, odds ratio; 95% CI, 95% confidence interval; HR, hazard ratio; AP3no-ox, APACHE III score with oxygenation component removed; bAPACHE III risk of death with oxygen component removed from calculation algorithm; ctreatment limitation order or palliative care coded for the patient. Indigenous status was removed from both models for nonsignificance (P < 0.01): (OR 1.3 (95% CI, 1.0 to 1.8), P = 0.04), (HR 1.1 (95% CI, 0.9 to 1.1) P = 0.89).