Figure 3.

Fluorescence-guided resection of tumors labeled with GFP in situ. (A) Peritoneal disseminated nodules were labeled by GFP expression 5 d after OBP-401 virus administration. (B) Laparotomy was performed. (C) Disseminated nodules labeled with GFP were removed under GFP-guided surgical navigation. (D) Disseminated nodules removed under GFP-guided navigation. Top, bright field observation; Bottom, fluorescent detection. (E) Section of disseminated nodules. Top, H&E section; Bottom, frozen section with fluorescence detection.