Table 2.
Time Point (day p.i.) | |||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Topological Metric | 1(day p.i.) | 2(day p.i.) | 3(day p.i.) | 4(day p.i.) | 5(day p.i.) | ||||||||||||||||||||
Rank | 1 | 2 | 3 | 4 | 5 | 1 | 2 | 3 | 4 | 5 | 1 | 2 | 3 | 4 | 5 | 1 | 2 | 3 | 4 | 5 | 1 | 2 | 3 | 4 | 5 |
Hubba MNC | 17 | 18 | 24 | 15 | 0 | 17 | 18 | 15 | 24 | 25 | 17 | 25 | 15 | 18 | 24 | 17 | 25 | 15 | 24 | 18 | 25 | 24 | 15 | 17 | 18 |
Hubba EPC | 17 | 18 | 24 | 15 | 20 | 17 | 24 | 15 | 18 | 25 | 17 | 25 | 15 | 24 | 18 | 17 | 25 | 15 | 24 | 18 | 25 | 15 | 24 | 18 | 17 |
Hubba DMNC | 0 | 10 | 4 | 6 | 7 | 11 | 14 | 20 | 32 | 0 | 2 | 11 | 12 | 22 | 31 | 31 | 0 | 4 | 10 | 7 | 0 | 11 | 22 | 28 | 31 |
Hubba Degree | 17 | 18 | 24 | 15 | 0 | 17 | 18 | 15 | 24 | 25 | 17 | 15 | 25 | 18 | 24 | 17 | 25 | 15 | 18 | 24 | 25 | 24 | 15 | 18 | 17 |
Hubba BN | 17 | 18 | 15 | - | - | 17 | 15 | - | - | - | 18 | 17 | 15 | 24 | - | 17 | 18 | 15 | 24 | - | 18 | 24 | 15 | 17 | 20 |
Indegree | 10 | 11 | 7 | 9 | 22 | 11 | 14 | 9 | 32 | 17 | 10 | 11 | 32 | 8 | 9 | 10 | 11 | 24 | 23 | 32 | 10 | 11 | 14 | 23 | 9 |
Outdegree | 17 | 18 | 24 | 15 | 3 | 17 | 18 | 15 | 24 | 25 | 17 | 15 | 25 | 18 | 24 | 17 | 25 | 15 | 24 | 18 | 25 | 15 | 24 | 18 | 17 |
Betweenness Centrality | 17 | 18 | 15 | 24 | 33 | 17 | 18 | 15 | 20 | 25 | 17 | 18 | 29 | 15 | 25 | 17 | 25 | 18 | 23 | 15 | 18 | 17 | 25 | 15 | 23 |
Clusters were evaluated in every time point with several topological metrics as defined in Hubba analyzer. Also, the indegree, outdegree and betweenness centrality scores were calculated with the use of Cytoscape plugins. We display the top 5 clusters (with descending rank order) at every time point with the highest scores in every metric, with the exception of BN metric where only few clusters had score > 0.