Table 2.

Top Scorer Clusters

					Time Point (day p.i.)
Topological Metric	1(day p.i.)					2(day p.i.)					3(day p.i.)					4(day p.i.)					5(day p.i.)
Rank	1	2	3	4	5	1	2	3	4	5	1	2	3	4	5	1	2	3	4	5	1	2	3	4	5
Hubba MNC	17	18	24	15	0	17	18	15	24	25	17	25	15	18	24	17	25	15	24	18	25	24	15	17	18
Hubba EPC	17	18	24	15	20	17	24	15	18	25	17	25	15	24	18	17	25	15	24	18	25	15	24	18	17
Hubba DMNC	0	10	4	6	7	11	14	20	32	0	2	11	12	22	31	31	0	4	10	7	0	11	22	28	31
Hubba Degree	17	18	24	15	0	17	18	15	24	25	17	15	25	18	24	17	25	15	18	24	25	24	15	18	17
Hubba BN	17	18	15	-	-	17	15	-	-	-	18	17	15	24	-	17	18	15	24	-	18	24	15	17	20
Indegree	10	11	7	9	22	11	14	9	32	17	10	11	32	8	9	10	11	24	23	32	10	11	14	23	9
Outdegree	17	18	24	15	3	17	18	15	24	25	17	15	25	18	24	17	25	15	24	18	25	15	24	18	17
Betweenness Centrality	17	18	15	24	33	17	18	15	20	25	17	18	29	15	25	17	25	18	23	15	18	17	25	15	23

Clusters were evaluated in every time point with several topological metrics as defined in Hubba analyzer. Also, the indegree, outdegree and betweenness centrality scores were calculated with the use of Cytoscape plugins. We display the top 5 clusters (with descending rank order) at every time point with the highest scores in every metric, with the exception of BN metric where only few clusters had score > 0.