Table 1.
IQ scores of patients and controls at each time period
| Number tested | Mean adjusted IQ* (SD) | Difference in means (95% CI) |
t-test p-value |
|||
|---|---|---|---|---|---|---|
| Controls | Patients | Controls | Patients | |||
| FSIQ | ||||||
| 5 months | 157 | 284 | 102.5 (14) |
101.0 (15) |
1.4 (-1.5 : 4.4) |
0.3 |
| 3 years | 173 | 366 | 104.8 (14) |
97.7 (16) |
7.1 (4.4 : 9.8) |
< 0.0001 |
| 5 years | 132 | 289 | 105.2 (15) |
100.0 (16) |
5.2 (1.9 : 8.5) |
0.002 |
| VIQ | ||||||
| 5 months | 158 | 287 | 102.0 (14) |
99.6 (15) |
2.3 (-0.5 : 5.2) |
0.1 |
| 3 years | 173 | 366 | 103.4 (15) |
97.7 (15) |
5.7 (3.1 : 8.4) |
< 0.0001 |
| 5 years | 132 | 289 | 103.2 (14) |
99.6 (15) |
3.6 (0.5 : 6.7) |
0.02 |
| PIQ | ||||||
| 5 months | 160 | 299 | 102.5 (15) |
102.0 (16) |
0.5 (-2.5 : 3.5) |
0.7 |
| 3 years | 173 | 368 | 105.5 (15) |
98.2 (16) |
7.3 (4.5 : 10.1) |
< 0.0001 |
| 5 years | 132 | 289 | 106.4 (16) |
100.5 (17) |
5.9 (2.5 : 9.3) |
0.0006 |
*IQ adjusted for test by subtracting:
7.15 from each WPPSI-R full IQ
3.79 from each WPPSI-R verbal IQ.
8.74 from each WPPSI-R performance IQ.