Skip to main content
. 2011 Nov 17;7(11):e1002391. doi: 10.1371/journal.pgen.1002391

Figure 2. XBP-1 deficiency increases PEK-1 dependent phosphorylation of eIF2α.

Figure 2

(A) PEK-1 dependent phosphorylation of eIF2α is induced by high dose (50 ug/ml) tunicamycin. Western blot of P-eIF2α, total eIF2α and tubulin in WT and pek-1(ok275) strains grown to the L4 stage and then shifted to plates with or without tunicamycin (50 µg/mL) for 4 hours. (B) PEK-1 dependent phosphorylation of eIF2α is induced by XBP-1 deficiency. Western blot of P-eIF2α, total eIF2α and tubulin in WT, xbp-1(tm2482), xbp-1(tm2482); pek-1(ok275) and pek-1(ok275) strains grown to the L4 stage.