Table 1. Clinical and laboratory characteristics by diagnosis of children with and without Plasmodium falciparum malaria – medians (ranges).
| CM Cerebral Malaria | MM Mild malaria | NMFI Non-malaria febrile illness controls | NFI Non-febrile illness controls | ||
| retinopathy positive | retinopathy negative | ||||
| Sample size | 79 | 20 | 59 | 32 | 17 |
| Sex1 female | 32 (40.5%) | 11 (55.0%) | 26 (44.1%) | 12 (38.7%) | 8 (47.1%) |
| male | 47 (59.5%) | 9 (45.0%) | 33 (55.9%) | 19 (61.3%) | 9 (52.9%) |
| Age (months)2 | 34.5 (8.0–86.0) | 36.5 (17.0–164.0) | 24.0 (3.0–60.0) | 23.5 (6.0–60.0) | 23.0 (6.0–48.0) |
| Lactate (nM) | 6.9 (1.1–18.9) | 5.1 (1.2–21.4) | n.t. | n.t. | n.t. |
| Platelets (104/µl)3 | 5.2 (0.5–26.6) | 12.5 (0.6–54.5) | 13.8 (2.9–31.6) | 34.1 (27.4–58.0) | n.t. |
| Haemoglobin (g/dl)4 | 6.1 (2.5–10.0) | 9.2 (4.3–12.9) | 7.9 (3.6–12.8) | 10.3 (7.0–12.5) | n.t. |
| Parasitaemia (103/µl)5 | 51.5 (0.1–1149.4) | 58.8 (0.2–725.9) | n.t. | n.t. | n.t. |
| VWF (nM) | 191.1 (40.5–484.3) | 171.9 (110.1–427.2) | 117.2 (64.4–355.3) | 72.3 (20.4–142.7) | 37.1 (9.3–62.1) |
| VWFpp (nM) | 28.4 (4.8–107.5) | 33.2 (9.0–80.0) | 18.3 (5.1–53.2) | 9.3 (2.3–22.3) | 3.4 (1.0–30.6) |
n.t.: not tested.
1
not recorded for 1 child in NMFI group.
2
not recorded for 1 child in CM retinopathy positive group.
3
not recorded for 5 children in CM retinopathy positive group, 1 child in CM retinopathy negative group, 10 children in MM group and 22 children in NMFI group.
4
not recorded for 10 children in MM group and 22 children in NMFI group.
5
not recorded for 2 children in CM retinopathy positive group and 1 child in CM retinopathy negative group.
Normal range for lactate: 0.7–2.1 nM.