Table 1. Diagnostic profiles of seven selected kiwifruit allergic patients used for the initial characterization of kiwifruit LTPs.
A. | |||||||||||
Subjects | InterAll APC Code | Age | Gender | Symptoms° | Total IgE | Skin test* | CAP IgE** | DBPCFC° | ISAC 103 IgE** | ||
Commercial extract | Prick-Prick | Commercial extract | Act d 1 | Pru p 3 | |||||||
1 | ITROMIDI28837 | 26 | M | URT | 1254 | 18.00 | Neg | Neg | URT | Neg | 1.07 |
2 | ITROMIDI21272 | 40 | M | URT | 790 | Neg | Neg | 4.10 | URT | Neg | 1.01 |
3 | ITROMIDI24698 | 37 | F | OAS | 11 | 43.69 | 89.05 | 1.24 | URT | Neg | 3.61 |
4 | ITROMIDI24232 | 31 | F | GI - URT | 65 | Neg | 29.39 | 1.02 | GI - URT | Neg | 1.89 |
5 | ITROMIDI28626 | 16 | M | GI | 450 | Neg | 60.06 | 3.40 | URT | 4.34 | 9.35 |
6 | ITROMIDI1558 | 28 | M | GI - URT | 211 | 56.00 | 109.11 | 0.84 | GI - URT | Neg | 2.70 |
7 | ITROMIDI5272 | 27 | F | OAS | 2500 | 17.34 | 23.76 | 7.00 | URT | Neg | 5.46 |
Panel A: Tests leading to kiwifruit LTP suspected reactivity are reported.
APC: Allergome Personal Code used in the InterAll e-record.
° Double Blind Placebo Controlled Food Challenge; GI: gastro-intestinal tract symptoms including vomiting and abdominal pain; OAS: oral allergy syndrome; URT: Urticaria.
*Results of skin testing performed with green kiwifruit are expressed as mm2.
**ISAC and CAP IgE results are expressed as kU/l.
Panel B: In vivo and in vitro results of kiwifruit LTP testing are reported.
APC: Allergome Personal Code used in the InterAll e-record.
*Results of skin testing are expressed in mm2.
**ISAC and CAP IgE results are expressed as kU/l. A streptavidin-CAP has been used for kiwifruit LTP IgE detection.
°° In-house Pru p 3 preparation used throughout the study was immobilized on ISAC Exp96.