Table 1. Incubation periods in Tg(Sho) mice following inoculation with different prion strains.

		Mean incubation period ± s.e.m. (days)
Line	Relative Sho Expression Level	RML	n/n 0	Me7	n/n 0	301V	n/n 0
FVB	1×	129±3	8/8	144±2	8/8	193±2	7/7
Tg(MoSho)24474	12×	122±3	7/7	141±3	8/8	202±6	6/6
Tg(MoSho)24488	20×	122±1	8/8	nd	nd	nd	nd
Tg(HuSho)479	∼16x	119±4	7/7	nd	nd	nd	nd
Tg(HuSho)3930	∼32x	118±2	7/7	nd	nd	nd	nd

n, number of ill mice; n ₀, number of inoculated mice. nd, not determined.