Table 2.
Distribution of ABCA haplotypes and genotypes
Polymorphism | Genotypes/Haplotypes |
Control Group n = 93 |
PCOS Group n = 98 |
OR* | 95% CI* | P* |
---|---|---|---|---|---|---|
G1051A | GG (Wild type) | 34 36,6% |
30 31,2% |
R | 0.585 | |
GA (Heterozygote) | 49 52,7% |
53 53,8% |
0,836 | 0,444-1,574 | 0,579 | |
AA (Mutant) | 10 10,8% |
15 15,1% |
0,609 | 0,235-1,577 | 0,307 | |
G | 117 62,9% |
114 58,1% |
0.817 | 0.538-1.238 | 0.396 | |
A | 69 37,1% |
82 41,9% |
||||
G2706A | GG (Wild type) | 55 60,7% |
80 82,6% |
R | 0.004 | |
GA (Heterozygote) | 30 32,1% |
9 8,7% |
5,029 | 1,922-13,160 | 0.001 | |
AA (Mutant) | 8 7,1% |
9 8,7% |
1,118 | 0,339-3,685 | 0.855 | |
G | 162 87,0% |
150 76,8% |
2.016 | 1.094-3.714 | 0.027 | |
A | 24 13,0% |
46 23,2% |