Figure 1. SDF-1α up-regulates PDGF-B protein expression in TC/siVEGF7-1 tumors.
Immunohistochemistry analysis for PDGF-B protein. TC/siVEGF7-1 tumors in vivo were injected with either Ad-SDF-1α or Ad-control 2 times weekly for 3 weeks. On day 23 after tumor cell inoculation, tumors were resected, placed in OCT, and snap-frozen in liquid nitrogen. Tumor sections were cut, fixed, and analyzed for expression of PDGF-B by immunohistochemistry (brown staining). Ad-SDF-1α up-regulates PDGF-B protein levels compared with Ad-control.