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Treatment response estimated with DSC perfusion imaging with gadodiamide (left) and ferumoxytol (right). With gadodiamide, the percentage decrease in tumor rCBV after antiangiogenic treatment varies among no preload, single-dose (s.d.) preload, and double-dose (d.d.) preload groups in each individual rat (n = 6). Conversely, with use of ferumoxytol, treatment response is the same regardless of preload dose.
