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. Author manuscript; available in PMC: 2011 Nov 18.
Published in final edited form as: Toxicol Appl Pharmacol. 2010 Jun 11;247(2):105–115. doi: 10.1016/j.taap.2010.06.003

Figure 5.

Figure 5

Modification of OVA-tg T-cell differentiation with spleen cells from stat4−/− DO11.10+/− (a), stat6−/− DO11.10+/− (b), or wild type DO11.10+/− (c) mice. Cells were differentiated with OVA in the absence of various additives (black circle) or presence of TGF-β (open circle), anti-IL-4 (black triangle), anti-IL-12 (open triangle), Pb (black square), TGF-β+anti-IL-4 (open square), TGF-β+anti-IL-12 (black diamond), or Pb+anti-IL-4 (open diamond). Data were obtained from 6 mice assayed individually in six separate experiments, and the results are expressed as the mean amounts (± SEM) of IL-4 and IFN-γ produced.