TABLE 1.

Body and liver weights and plasmatic parameters of 6 h–fasted L-g6pc^−/− mice

	L-g6pc−/−	L-g6pc+/+
Mice per group	6	6
Body wt (g)	27.8 ± 0.8	26.5 ± 0.8
Liver wt (g)	1.8 ± 0.04**	1.1 ± 0.1
Glucose (mmol/L)	3.4 ± 0.2**	7.2 ± 0.3
Insulin (ng/mL)	0.35 ± 0.02**	0.67 ± 0.07
Glucagon (pg/mL)	552 ± 50**	302 ± 28
Corticosterone (ng/mL)	191 ± 19**	71.0 ± 9.7
Norepinephrine (ng/mL)	0.43 ± 0.06	0.43 ± 0.03
Epinephrine (ng/mL)	0.36 ± 0.10	0.36 ± 0.04
Total cholesterol(g/L)	1.33 ± 0.09**	0.89 ± 0.04
Triglycerides (g/L)	1.42 ± 0.1**	0.78 ± 0.03
Free fatty acids (mmol/L)	1.07 ± 0.09**	0.69 ± 0.06
Glycerol (mg/dL)	4.3 ± 0.2	4.2 ± 0.3
Lactate (mmol/L)	5.5 ± 0.5**	3.5 ± 0.3
Alanine (µmol/L)	336 ± 34**	224 ± 18
Glutamine (µmol/L)	538 ± 16*	618 ± 26

Values are expressed as means ± SEM. Data were determined 5 weeks after gene invalidation from L-g6pc^−/− and WT L-g6pc^+/+ mice upon 6 h of fasting.

Values significantly different from WT (*P < 0.05 and **P < 0.01) are indicated (Mann-Whitney test).