Table 4.
NFKBIL2 and flanking gene polymorphism allele frequencies: European IPD and African bacteraemia case-control studies
| Polymorphism/location | UK Caucasian study | Kenyan study | ||
|---|---|---|---|---|
| Minor allele frequency (%) | P valuea | Minor allele frequency (%) | P valuea | |
| rs10448143, -5,224 | 24.3 | 0.537 | 4.7 | 0.250b |
| rs2170096, -4,368 | 49.6 | 0.085 | 38.2 | 0.145 |
| rs4925858, -3,771 | 47.1 | 0.036 | 30.7 | 0.128 |
| rs760477, -263 | 48.1 | 0.007 | 25.7 | 0.009 |
| rs2306384, +2,754 | 49.8 | 0.002 | 33.5 | 0.427 |
| rs4082353, +12,589 | 48.5 | 0.007 | 33.4 | 0.857 |
| rs2272658, +16,899 | 49.9 | 0.035 | 36.7 | 0.927 |
| rs13258200, +36,964 | 37.0 | 0.833 | 40.2 | 0.801 |
| rs4380978, +68,695 | 42.5 | 0.893 | 32.6 | 0.648 |
aP values are derived from 3 × 2 chi-squared comparisons of genotypes (two degrees of freedom). bFisher's exact test (two-tailed). P values below 0.05 are highlighted in bold.