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. 2010 Dec 8;14(6):245. doi: 10.1186/cc9296

Table 1.

Factors affecting respiratory mechanics

Increased airway resistance Reduced compliance
Tube (small diameter, sputum retention) Chest wall
Central airways  Edema
 Tracheostomy malposition  Elevated abdominal pressure
 Sputum plug  Pleural fluid and ascites
 Corpus alienum (after trauma)  Obesity
 Tracheomalacia or tracheal stenosis Lung
Small airways  Intrinsic positive end-expiratory pressure
 Asthma and chronic obstructive pulmonary disease  Alveolar filling (edema, pus, and collapse)
 Acute respiratory distress syndrome  Pneumonia
 Interstitial lung disease and fibrosis