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. Author manuscript; available in PMC: 2011 Nov 18.
Published in final edited form as: Nat Protoc. 2011 Jul 21;6(8):1183–1191. doi: 10.1038/nprot.2011.361

Figure 1.

Figure 1

Picture of the standard hamster cage used in repeated social defeat stress experiments. The resident aggressor is permanently housed on one side of the perforated divider, and all defeats are performed within that compartment while rotating C57BL/6J intruders across defeat days so that these experimental animals do not habituate to a single aggressor. Note that care must be taken to ensure that the divider is firmly secure, thereby preventing mice from escaping their overnight compartments. Social defeat experiments must follow all governmental and institutional guidelines for care and use of laboratory animals.