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Oxidized HDL has inflammatory properties. The HDL inflammatory index was determined for three samples of FPLC-purified HDL from healthy volunteers in a cell-based assay as described in “Materials and Methods.” The same HDL samples were oxidized as described in “Materials and Methods” (oxHDL), and the HDL inflammatory index was determined. The oxidized HDL had significantly higher HDL inflammatory index (**P = 0.002, paired t-test).
