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. 2011 Aug 11;301(5):G856–G864. doi: 10.1152/ajpgi.00178.2011

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Fig. 4. — Assessment of markers of lineage-specific differentiation in PTEN^WT and PTEN^Lox/Lox/villin^Cre mice. A: alkaline phosphatase staining (absorptive cell lineage). B: alcian blue staining (goblet cell lineage, back arrowheads). C: hematoxylin and eosin (H&E) staining showing Paneth cells with the characteristic eosinophilic granules at the crypt base (white arrows) in duodenum (top) and jejunum (bottom). D: lysozyme staining (Paneth cell lineage). E: chromogranin A staining (enteroendocrine cell lineage).