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Rapid partitioning in a mixed Golgi. As soon as secretory cargoes enter the Golgi, they equilibrate across the stack via intercisternal continuities. Secretory cargoes partition dynamically between processing domains, which contain resident Golgi proteins, and export domains. These various domains are established by segregation of different lipid species. Secretory cargoes can exit the Golgi at every level of the stack.
