Figure 5.

Proteins in the vicinity of the E site of the large ribosomal subunit. Oligonucleotide analogs of the acceptor stem of a tRNA (orange) will bind to the E site of the large ribosomal subunit from H. marismortui. The proteins in the immediate neighborhood, L44e (green) and L15e (blue), have no homologs in the eubacterial ribosome. When the structure of the large ribosomal subunit from D. radiodurans (Harms et al. 2001) is superimposed on that of H. marismortui, it is found that L33 (red) and L31 (yellow) occupy suggestively similar positions. (Reproduced with permission from Schmeing et al. (2003).)