Table 2.

Clinical preimplantation genetic diagnosis results

Embryos	α-thalassemia		β-thalassemia					Outcomes
	Amplified signal (bp)	Diagnosis	PCR-RDB and fluorescent PCR		HumTH01		Diagnosis
			β-17 (mut/nor)	β-28 (mut/nor)	Pat (bp)	Mat (bp)
E1	178	Affected	NS X	NS X	127	115	Normal	NTE
E2	282	Normal	X ADO	NS X	127	127	β-17 carrier	ET
E3	178/282	Carrier	NS X	X ADO	119	127	β-28 carrier	ET
E4	178/282	Carrier	X X	NS X	127	127	β-17 carrier	NTE
E5	Amplification failure		NS X	NS X	127	115	Normal	NTE
E6	282	Normal	NS X	X ADO	119	ADO	β-28 carrier	ET

ADO allele drop out; NS no signal; X visible signal; mut mutant dot;nor normal dot; pat paternal allele; mat maternal allele; ET embryo transfer; NTE nontransferred embryos.