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. 2011 Sep 28;286(47):40889–40899. doi: 10.1074/jbc.M111.300988

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 1. — Sialic acid catabolism and the V. vulnificus nan cluster. A, schematic representation of the transport and catabolic pathway of sialic acid in bacteria is adopted from previously reported literature (8, 11). B, arrows represent the transcriptional directions and the coding regions of the V. vulnificus nan cluster. Gene names and locus tag numbers are based on the data base of the V. vulnificus MO6-24/O genome sequence (GenBank^TM accession numbers CP002469 and CP002470; see Ref. 40). Proposed gene products are as follows: nanR, a putative transcriptional regulator; nanA, Neu5Ac lyase; nanT_PSL, components of tripartite ATP-independent periplasmic type Neu5Ac transporter; nanE, N-acetylmannosamine-6-phosphate epimerase; nanK, N-acetylmannosamine kinase; nagA, N-acetylglucosamine-6-phosphate deacetylase.