Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Sep 14;286(47):40659–40670. doi: 10.1074/jbc.M111.260430

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

Author's Choice—Final version full access.

Creative Commons Attribution Non-Commercial License applies to Author Choice Articles

PMC Copyright notice

FIGURE 9. — Structural mapping of the HSPC038-ICln 1–159 interaction interfaces. a, overlay of ¹H-¹⁵N HSQC NMR spectra of free HSPC038 (blue contours) and the HSPC038-ICln 1159 complex (red contours). b, absolute difference in resonance frequency (Equation 1) between free HSPC038 and the HSPC038-ICln 1–159 complex displayed against the primary sequence. Secondary structure elements are indicated in blue (β-strands) and in red (α-helix). c, HSPC038 residues with a frequency difference exceeding 9 Hz (dotted line in b) upon complex formation with ICln 1–159 are colored in red on the HSPC038 homology model. The zinc coordinating cysteine and histidine residues are shown as blue sticks. d, overlay of ¹H-¹⁵N HSQC NMR spectra of free ICln 1–159 (blue contours) and the ICln 1–159-HSPC038 complex (red contours). e, absolute difference in resonance frequency (Equation 1) between free ICln 1–159 and the ICln 1–159-HSPC038 complex displayed against the primary sequence. Secondary structure elements are indicated in blue (β-strands) and in red (α-helix). f, ICln 1–159 residues with a frequency difference exceeding 10 Hz (dotted line in e) upon complex formation with HSPC038 are colored in red on conformer number one in Protein Data Bank code 1ZYI. Secondary structure elements defined previously (32) are indicated on the structure.