Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
DMPK localizes to the nuclear envelope. A–C, immunofluorescent labeling of DMPK (red) confirmed localization to the NE in HeLa cells. Scale bar = 10 μm in all panels. Staining of β-tubulin (A, green) showed cell size and shape. Colocalization with Lamin-A/C (B, green) and Lamin-B1 (C, green) confirmed DMPK at the NE. D, FL-DMPK-mCherry in HeLa cells (16-h transfection, red) colocalizes with Lamin-A/C (green). DAPI (blue) stained the nucleus in all overlay panels.
